Master of Science in Neuroscience - Cellular Neurosciences

The cells that comprise the nervous system are among the most remarkable in nature. The Neuroscience graduate program includes several laboratories with robust research programs in the cellular aspects of neuroscience. We are addressing fundamental questions such as how axons grow, branch and navigate during development, how dendrites become different from axons, and how neurons migrate from their sites of origin to their final destinations in the developing brain. These questions are addressed using contemporary molecular biological techniques, biochemistry, primary cell culture, cutting-edge microscopy including live-cell imaging, as well as in vivo models including genetic mice and Drosophila. Studies are focused on cytoskeletal elements including microtubules and actin filaments, signaling pathways, local protein synthesis, axonal transport and synaptic transmission. All of the cellular neuroscientists in the program have robust pre-clinical disease and injury components in their research programs, with emphasis on diseases including Alzheimer's, hereditary spastic paraplegia, ALS, autism spectrum disorders, Gulf War illness, HIV-AIDS, multiple sclerosis and Parkinson's, as well as injuries including spinal cord injury and traumatic brain injury. Some of us are using stem cells and induced pluripotent cells from human patients with neurodegenerative diseases. The cellular neuroscientists at Drexel University have robust collaborations with systems and behavioral neuroscientists, clinical neuroscientists, biomedical engineers and cell biologists studying other cell types such as epithelial, immune and cancer cells.

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